Anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata

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Ju Sung Lee, Ah Young Lee, Norman G. Quilantang, Paul John L. Geraldino, Eun Ju Cho, Sanghyun Lee

2019 Journal of Applied Biological Chemistry Vol. 62 Issue 2 Article Cited by 20 Quartile

Abstract

This study evaluated the anti-oxidant activity of avicularin and isovitexin from Lespedeza cuneata using 2,2-diphenyl-1picrylhydrazyl (DPPH) and hydroxyl (OH) scavenging assays. The results showed that among the four fractions, the highest OH radical scavenging activity was exhibited by the n-butanol fraction. The DPPH radical scavenging activities of avicularin and isovitexin were higher than 50% at a concentration of 100 μg/mL. Moreover, one hundred micrograms per liter of avicularin and isovitexin exhibited effective anti-oxidant activity, with the OH radical scavenging rates being 87.54 and 91.48%, respectively. These results suggest that Lespedeza cuneata would be useful anti-oxidant agents from natural sources. © The Korean Society for Applied Biological Chemistry 2019.

Affiliations

Department of Plant Science and Technology, Chung-Ang University, Anseong, 17546, South Korea; Department of Food Science, Gyeongnam National University of Science and Technology, Jinju, 52725, South Korea; Department of Biology, University of San Carlos, Cebu, 6000, Philippines; Department of Food Science and Nutrition, Pusan National University, Busan, 46241, South Korea