Juree Kim, Leo Adrianne Paje, Jung Won Choi, Hak-Dong Lee, Jae Suk Shim, Jeehyoung Shim, Paul John L. Geraldino, Sanghyun Lee
Silymarin (SM) and silybin diastereomers (SD) in milk thistle (Silybum marianum) were determined using highperformance liquid chromatography and quantified using a reverse-phase column in a gradient elution system. UV detection was performed at 288 nm. The content of SM and SD in milk thistle was 3.236 and 0.553 mg/g DW, respectively. Determining the presence and quantifying the content of SM and SD in milk thistle are vital for the pharmaceutical industry to identify optimal sources for developing health supplements or therapeutics. © 2020, Korean Society of Pharmacognosy. All rights reserved.
Department of Plant Science and Technology, Chung-Ang University, Anseong, 17546, South Korea; Imsil Herbal Medicine Association, Imsil, 55955, South Korea; EL&I Co., Ltd., Gimje, 54318, South Korea; Department of Biology, University of San Carlos, Cebu, 6000, Philippines
